Tsugafolin waa flavonoid, oo ah nooc ka mid ah polyphenol-ka cuntada ee si weyn looga helo dhir badan, oo ay ku jiraan geedo yaryar, sida geed kedar ah oo Jabbaan ah (Cryptomeria japonica), oo ku korta genus Tsuga. Daraasado hore ayaa soo jeediyay in flavonoids ay yeelan karaan faa'iidooyin caafimaad, oo ay ku jiraan anti-bararka, antioxidant, iyo saamaynta kansarka.
Si loo tijaabiyo awoodda ka hortagga kansarka ee Tsugafolin, cilmi-baarayaashu waxay go'doomiyeen xarunta caleemaha Tsuga sieboldii, oo ah geed Japanese weligood cagaar ah. Waxay dabadeed tijaabiyeen saamaynta xarunta dhowr khadadka unugyada kansarka ee aadanaha, oo ay ku jiraan kansarka sambabada, kansarka beerka, kansarka mindhicirka, iyo kansarka naasaha. Natiijooyinku waxay muujiyeen in Tsugafolin uu lahaa cytotoxicity awood leh, ama awood-dilka unugyada, liddi ku ah unugyada kansarka, oo leh qiimayaasha IC50 u dhexeeya 0.8 ilaa 16.9 μM.
Tijaabooyin dheeraad ah ayaa shaaca ka qaaday in Tsugafolin ay keentay apoptosis, ama dhimashada unugyada barnaamijka, ee unugyada kansarka, iyo sidoo kale xannibay guuritaanka unugyada iyo duulaanka, labaduba waa geedi socod muhiim ah oo ku saabsan metastasis-ka kansarka. Waxaa intaa dheer, Tsugafolin waxaa lagu ogaadey inuu xakameynayo muujinta borotiinnada kala duwan ee ku lug leh dariiqyada calaamadaha kansarka, sida AKT, ERK, iyo STAT3.
Helitaanka Tsugafolin oo ah xarun ka hortag ah oo dabiici ah ayaa furi karta dariiqyo cusub oo loogu talagalay daaweynta kansarka iyo ka hortagga. Si ka duwan dawooyinka synthetic, xeryahooda dabiiciga ah ayaa faa'iido u leh inay guud ahaan ammaan yihiin oo si fiican u dulqaadanayaan jidhka bini'aadamka, waxayna sidoo kale bixin karaan habab dhismeed cusub oo loogu talagalay naqshadaynta daroogada. Si kastaba ha ahaatee, cilmi baaris dheeraad ah ayaa loo baahan yahay ka hor inta aan Tsugafolin loo samaynin daawo caafimaad oo loogu talagalay daaweynta kansarka.
